|Education||BS, National University of Singapore|
The structure of neural systems in the mammalian brain is dictated by tightly regulated cell generation and migration patterns during early development. These include layered structures such as the neocortex and cerebellum, and nuclear structures like the hypothalamus and thalamus. Although the organization of layered structures has been well-studied, it remains unclear as to how nuclear structures in the brain are formed. I am interested in decoding the heterogeneity of stem cells in nuclear brain structures at single-cell resolution using methods such as lineage tracing by clonal analysis and single-cell RNA seq of neural stem cells.