|Education||BS, Drew University|
|Current Position||Postdoctoral fellow|
German Center for Neurodegenerative Diseases
I am interested in contributing to the development of disease-modifying therapeutics for Alzheimer’s disease (AD) by addressing etiologic diversity in specific emerging sub-populations of patients. My current work uses transgenic modeling and molecular biology techniques to investigate the potential contribution of disease-related pathologies to the etiology of Alzheimer’s disease. My current focus is on the RNA-binding protein TDP43, which is observed in cytoplasmic inclusions with accompanying loss of nuclear expression in sub-populations of patients with Alzheimer’s, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). Using transgenic mouse models of amyloidosis and samples from human patients, I am investigating the potential involvement of this loss of TDP43 in the etiology and progression of Alzheimer’s disease.