|Education||BS, North Carolina Central University|
|Current Position||ORISE Postdoctor Fellow|
Defining therapeutic targets to inhibit pathologic hypertrophy
Heart failure is defined as the inability of the heart to meet the demands of the body. In many instances, heart failure results from pathologic ventricular hypertrophy which is followed by cardiac dilation. Previously, my lab reported that the activation of the protein kinase G (PKG) pathway blocks hypertrophic signaling and leads to reverse remodeling in mouse models. My thesis work will focus on defining the downstream targets of PKG signaling, as well as identifying novel therapeutic targets.