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Christa Wagner

Class 2010
Education BA, Oberlin College

Dr. Mary Armanios

Current Position Postdoctoral fellow

Johns Hopkins University

Research Interests

My research focuses on understanding the cancer-prone basis of the premature aging disorder dyskeratosis congenita. Dyskeratosis congenita patients have defects in telomere maintenance and are prone to developing cancers in several organs, including the skin and bone marrow. Using a relevant mouse model, I am focused on modeling the genetics of these cancers in order to understand their underlying biology.


Alder JK, Stanley SE, Wagner CL, Hamilton M, Hanumanthu VS, Armanios M. Exome sequencing identifies mutant TINF2 in a family with pulmonary fibrosis. Chest. 2015 May;147(5):1361-8. doi: 10.1378/chest.14-1947. PMID: 25539146

Silhan LL, Shah PD, Chambers DC, Snyder LD, Riise GC, Wagner CL, Hellström-Lindberg E, Orens JB, Mewton JF, Danoff SK, Arcasoy MO, Armanios M. Lung transplantation in telomerase mutation carriers with pulmonary fibrosis. Eur Respir J. 2014 Jul;44(1):178-87. doi:10.1183/09031936.00060014. Epub 2014 May 15. PMID: 24833766

Alder JK, Parry EM, Yegnasubramanian S, Wagner CL, Lieblich LM, Auerbach R, Auerbach AD, Wheelan SJ, Armanios M. Telomere phenotypes in females with heterozygous mutations in the dyskeratosis congenita 1 (DKC1) gene. Hum Mutat. 2013 Nov;34(11):1481-5. doi: 10.1002/humu.22397. Epub 2013 Sep 11. PMID: 23946118