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Brian Goh

Class 2011
Education BS, Louisiana State University
Email bgoh1@jhmi.edu
Mentor

Dr. Tom Clemens

Research Interests

Musculoskeletal diseases such as osteoporosis, low bone mass, and sarcopenia, low muscle mass, are significant contributors to frailty in our aging population. Skeletal muscle mass and bone volume are very closely related, suggesting that there may be common anabolic signaling between these two adjacent tissues. Because the activin receptor pathway has been shown to be a strong regulator of skeletal muscle mass, likewise, I am investigating the role of activin receptor signaling in regulating bone development, maintenance, and regeneration. Using pharmacological and genetic approaches, I am examining how activin receptor signaling modulates bone mass, with the hopes of better understanding the musculoskeletal diseases that affect each of these tissues.