|Education||BS, Pennsylvania State University|
|Current Position||Postdoctoral fellow|
Johns Hopkins University
We are looking at muscle regeneration in the context of both muscle injuries and also muscle diseases including muscular dystrophy. I am setting out to do this two ways – first, I am modulating nitric oxide signaling pharmacologically to try to increase fiber size and myogenic regulatory factor expression, and second, I am attempting to characterize a gene that is putatively a transcription factor playing an important role in muscle development and regeneration, both in cell culture and also in a mouse model.
Mammalian Mss51 is a skeletal muscle-specific gene modulating cellular metabolism. Moyer AL, Wagner KR. J Neuromuscul Dis. 2015;2(4):371-385. Epub 2015 Sep 21. PMID:26634192
Maturation of the human papillomavirus 16 capsid. Cardone G, Moyer AL, Cheng N, Thompson CD, Dvoretzky I, Lowy DR, Schiller JT, Steven AC, Buck CB, Trus BL. MBio. 2014 Aug 5;5(4):e01104-14. doi: 10.1128/mBio.01104-14. PMID:25096873
Incomplete degeneration versus enhanced regeneration in skeletal muscle. Moyer AL, Wagner KR. J Biol Chem. 2012 Jul 20;287(30):25549; author reply 25550. doi: 0.1074/jbc.L112.380923. No abstract available. PMID:22821807
Regeneration versus fibrosis in skeletal muscle. Moyer AL, Wagner KR. Curr Opin Rheumatol. 2011 Nov;23(6):568-73. doi: 10.1097/BOR.0b013e32834bac92. Review. PMID:21934499