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Mary Armanios, MD

Department Affiliations Oncology
Rank Associate Professor
Office Phone 410-955-8964
Lab Phone
Fax 410-614-2987
Email marmani1@jhmi.edu
SOM Address 186A, Cancer Research Building I
Website
Students

Christa Wagner 2010 – 2016

Susan Stanley 2011

Research Interests

Dr. Armanios developed an interest in the genetics of inherited syndromes of telomere shortening. She has been on the Johns Hopkins faculty since 2005 and her current research aims to bridge basic knowledge of telomere biology to clinically relevant paradigms.

Publications

Research Profile

  • Gimm O, Armanios M, Dziema H, Neuman HPH, Eng C. Somatic and occultgerm-line mutations in SDHD, a mitochondrial complex II gene, in nonfamilialpheochromocytoma. Cancer Research 2000;60:6822-6825.
  • Qi L, Strong MA, Karim BO, Armanios M, Huso DL, Greider CW. Short telomeresand loss of Atm cooperatively increase telomere dysfunction and suppresstumorigenesis, Cancer Research 2003;63:8188-96.
  • Armanios M, Grossman SA, Yang S, White B, Orens J. Transmission ofglioblastoma multiforme after bilateral lung transplantation, Neuro-oncology2004;6259-63.
  • Armanios M, Xu R, Forastiere A, Haller D, Kugler J, Benson AB. AdjuvantChemotherapy for Resected Adenocarcinoma of the Esophagus, Gastroesophageal(GE) Junction and Cardia (E8296): A Phase II Trial of the EasternCooperative Oncology Group, Journal of Clinical Oncology 2004;22:4495-9.
  • Armanios M, Chen JL, Chang Y-P, Brodsky RA, Hawkins A, Griffin CA, EshlemanJR, Cohen AR, Chakravarti A, Hamosh A, Greider CW. Haploinsufficiency ofTelomerase Reverse Transcriptase Leads to Anticipation in Autosomal DominantDyskeratosis Congenita, Proceedings of the National Academy of Sciences 2005102(44):15960-4.
  • Hao L-Y, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW.Short Telomeres, Even in the Presence of Telomerase, Limit Tissue RenewalCapacity, Cell 2005 123:1121-31.

 

  • Armanios M and Greider CW. Telomerase and Cancer Stem Cells. Cold SpringHarbor Symposia on Quantitative Biology: Molecular Approaches to ControllingCancer, 2005 70: 205-08.8. Armanios M, Chen JL, Cogan JD, Alder JK, Ingersoll RG, Markin C, Lawson WE,Xie M, Vulto I, Phillips JA, Lansdorp PM, Greider CW, Loyd JE. TelomeraseMutations in Families with Idiopathic Pulmonary Fibrosis, New England Journal ofMedicine, in press.
  • Armanios MY, Chen JL, Cogan JD, Alder JK, Ingersoll RG, Markin C, Lawson WE, Xie M, Vulto I, Phillips JA, Lansdorp PM, Greider CW, Loyd JE. Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis, New England Journal of Medicine, 2007 316: 1317-26.
  • Alder JK, Chen JL, Lancaster L, Danoff S, Su SC, Cogan JD, Vulto I, Xie M, Qi X, Tuder, RM, Phillips JA 3rd, Lansdorp PM, Loyd JE, Armanios MY. Short telomeres in idiopathic pulmonary fibrosis and related disorders, in press PNAS 105(35):13051-6, 2008.